Overview
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
6.7
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin D2 (as Ergocalciferol)
25 mcg (1,000 IU)
125%
Top Medical Research Studies
9.5
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
Read More
8
We conducted a randomized controlled trial to investigate how vitamin D supplementation might alleviate lower back pain in patients suffering from lumbar spinal stenosis. This study involved patients with severely low vitamin D levels, specifically under 10 ng/mL. Participants were divided into two groups: one received vitamin D supplements, while the other did not.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
Read More
2
We examined the effectiveness of vitamin D supplementation for people dealing with chronic low back pain (CLBP). Through a systematic review of randomized controlled trials, we focused on understanding whether vitamin D could bring any relief to those suffering from this persistent discomfort.
Our analysis of ten trials found that vitamin D supplementation did not lead to significant reductions in pain levels compared to control groups. This held true regardless of participants' initial vitamin D levels, and even long-term use did not show considerable improvements in pain outcomes. Interestingly, using active forms of vitamin D also failed to provide the hoped-for relief.
Despite these findings, it’s important to note that vitamin D might still play a role in a broader treatment plan for CLBP. However, as of now, there isn’t enough evidence to suggest that it can independently alleviate the pain. Further investigation is necessary to understand the potential long-term effects and the reasons behind the lack of benefit observed in our study.
Our analysis of ten trials found that vitamin D supplementation did not lead to significant reductions in pain levels compared to control groups. This held true regardless of participants' initial vitamin D levels, and even long-term use did not show considerable improvements in pain outcomes. Interestingly, using active forms of vitamin D also failed to provide the hoped-for relief.
Despite these findings, it’s important to note that vitamin D might still play a role in a broader treatment plan for CLBP. However, as of now, there isn’t enough evidence to suggest that it can independently alleviate the pain. Further investigation is necessary to understand the potential long-term effects and the reasons behind the lack of benefit observed in our study.
Read More
Most Useful Reviews
9
Returned shoulder pain
2 people found this helpful
It came back again and it's worse. Initially, my shoulder pain disappeared in days. However, after forgetting to take it for one day, the pain returned, and it's worse now.
Read More
9
No more back pain
Another great Now product. The capsules are small and straightforward to swallow, and they seem effective. I usually experience leg pain when my vitamin D is low, but since starting this, I haven't had any leg pain or back pain.
Read More
6
Reduced back pain
Works well for me. I live far north and work nights, leading to low vitamin D levels in my blood tests. These capsules helped elevate my levels to normal. They are small and easy to swallow; I took two a day for a month as per my doctor's advice. I haven't had any sniffles since starting them, and I've noticed some alleviation of joint and muscle pains, including back pain. Overall, I will purchase this again.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
6.7
- All Researches
9.5
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
Read More
9
We conducted a retrospective review to uncover how vitamin D treatment impacts back pain in individuals diagnosed with adult-onset hypophosphatemic osteomalacia. In our exploration, we found that eight patients, primarily experiencing widespread musculoskeletal pain, were assessed over a span from January 2011 to December 2019.
Each patient presented with low phosphorus levels, elevated alkaline phosphatase, and indicative imaging results. Notably, back pain was reported as the most common complaint, along with muscle weakness in over half of the cases. Our findings highlighted the effectiveness of vitamin D in tandem with phosphorus supplementation, as all patients reported significant improvements in pain, muscle strength, and gait after receiving treatment.
Importantly, we noted that the specific diagnosis of each patient varied. In six cases, treatment was prompted by adefovir-induced Fanconi syndrome, while the remaining two patients had tumor-induced osteomalacia and light-chain nephropathy. This variation indicates the diverse etiologies of hypophosphatemic osteomalacia, further emphasizing the importance of targeted treatment based on individual needs.
In conclusion, our study suggests that vitamin D, especially when combined with phosphorus, plays a crucial role in alleviating back pain associated with this condition. By enhancing the understanding of the relationship between vitamin D treatment and back pain, we aim to shed light on effective management strategies for those suffering from similar symptoms.
Each patient presented with low phosphorus levels, elevated alkaline phosphatase, and indicative imaging results. Notably, back pain was reported as the most common complaint, along with muscle weakness in over half of the cases. Our findings highlighted the effectiveness of vitamin D in tandem with phosphorus supplementation, as all patients reported significant improvements in pain, muscle strength, and gait after receiving treatment.
Importantly, we noted that the specific diagnosis of each patient varied. In six cases, treatment was prompted by adefovir-induced Fanconi syndrome, while the remaining two patients had tumor-induced osteomalacia and light-chain nephropathy. This variation indicates the diverse etiologies of hypophosphatemic osteomalacia, further emphasizing the importance of targeted treatment based on individual needs.
In conclusion, our study suggests that vitamin D, especially when combined with phosphorus, plays a crucial role in alleviating back pain associated with this condition. By enhancing the understanding of the relationship between vitamin D treatment and back pain, we aim to shed light on effective management strategies for those suffering from similar symptoms.
Read More
8
Effectiveness of combined treatments
We explored how a combination of treatments, including a specific vitamin D supplement (Cholecalciferol), could help alleviate back pain in young people suffering from sciatica due to herniated discs. In this study, we looked at 128 patients divided into three groups. One group received a combination of rehabilitation therapy and daily supplements, while the second group only underwent rehabilitation. The third group was given supplements without the additional therapy.
Over a span of 60 days, we measured improvements in pain levels, disability, and quality of life using various rating scales. We found that the group receiving both rehabilitation and supplements saw significant improvements in pain and overall quality of life after 30 days. However, after two months, while they still had better outcomes in pain and quality of life compared to the other groups, the vitamin D's individual effect couldn’t be distinctly isolated.
Ultimately, our findings suggest that while vitamin D was part of an effective treatment plan that included other beneficial supplements, we cannot attribute all the improvements in back pain directly to vitamin D alone. This highlights the importance of comprehensive treatment approaches for conditions like sciatica.
Over a span of 60 days, we measured improvements in pain levels, disability, and quality of life using various rating scales. We found that the group receiving both rehabilitation and supplements saw significant improvements in pain and overall quality of life after 30 days. However, after two months, while they still had better outcomes in pain and quality of life compared to the other groups, the vitamin D's individual effect couldn’t be distinctly isolated.
Ultimately, our findings suggest that while vitamin D was part of an effective treatment plan that included other beneficial supplements, we cannot attribute all the improvements in back pain directly to vitamin D alone. This highlights the importance of comprehensive treatment approaches for conditions like sciatica.
Read More
8
We conducted a randomized controlled trial to investigate how vitamin D supplementation might alleviate lower back pain in patients suffering from lumbar spinal stenosis. This study involved patients with severely low vitamin D levels, specifically under 10 ng/mL. Participants were divided into two groups: one received vitamin D supplements, while the other did not.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
Read More
8
We examined the impact of vitamin D treatment on patients experiencing back pain related to celiac disease. In one noteworthy case, a 66-year-old man sought help for persistent back and knee pain. After thorough testing, he was diagnosed with celiac disease, alongside vitamin D deficiency and low bone mineral density due to osteomalacia.
The treatment plan included a gluten-free diet and supplementation with vitamin D and calcium. Remarkably, over a span of six months, the patient reported immense relief from symptoms, along with improvements in bone mineral density.
Our findings highlight a significant link between vitamin D supplementation and improvements in musculoskeletal symptoms, particularly for those struggling with celiac disease. While we note that this case does not allow us to make definitive conclusions about vitamin D's isolated effects on back pain, it certainly suggests potential benefits worth considering.
The treatment plan included a gluten-free diet and supplementation with vitamin D and calcium. Remarkably, over a span of six months, the patient reported immense relief from symptoms, along with improvements in bone mineral density.
Our findings highlight a significant link between vitamin D supplementation and improvements in musculoskeletal symptoms, particularly for those struggling with celiac disease. While we note that this case does not allow us to make definitive conclusions about vitamin D's isolated effects on back pain, it certainly suggests potential benefits worth considering.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Returned shoulder pain
2 people found this helpful
It came back again and it's worse. Initially, my shoulder pain disappeared in days. However, after forgetting to take it for one day, the pain returned, and it's worse now.
Read More
9
No more back pain
Another great Now product. The capsules are small and straightforward to swallow, and they seem effective. I usually experience leg pain when my vitamin D is low, but since starting this, I haven't had any leg pain or back pain.
Read More
6
Reduced back pain
Works well for me. I live far north and work nights, leading to low vitamin D levels in my blood tests. These capsules helped elevate my levels to normal. They are small and easy to swallow; I took two a day for a month as per my doctor's advice. I haven't had any sniffles since starting them, and I've noticed some alleviation of joint and muscle pains, including back pain. Overall, I will purchase this again.
Read More
Frequently Asked Questions
9
No more back pain
Another great Now product. The capsules are small and straightforward to swallow, and they seem effective. I usually experience leg pain when my vitamin D is low, but since starting this, I haven't had any leg pain or back pain.
6
Reduced back pain
Works well for me. I live far north and work nights, leading to low vitamin D levels in my blood tests. These capsules helped elevate my levels to normal. They are small and easy to swallow; I took two a day for a month as per my doctor's advice. I haven't had any sniffles since starting them, and I've noticed some alleviation of joint and muscle pains, including back pain. Overall, I will purchase this again.
2
We examined the effectiveness of vitamin D supplementation for people dealing with chronic low back pain (CLBP). Through a systematic review of randomized controlled trials, we focused on understanding whether vitamin D could bring any relief to those suffering from this persistent discomfort.
Our analysis of ten trials found that vitamin D supplementation did not lead to significant reductions in pain levels compared to control groups. This held true regardless of participants' initial vitamin D levels, and even long-term use did not show considerable improvements in pain outcomes. Interestingly, using active forms of vitamin D also failed to provide the hoped-for relief.
Despite these findings, it’s important to note that vitamin D might still play a role in a broader treatment plan for CLBP. However, as of now, there isn’t enough evidence to suggest that it can independently alleviate the pain. Further investigation is necessary to understand the potential long-term effects and the reasons behind the lack of benefit observed in our study.
Our analysis of ten trials found that vitamin D supplementation did not lead to significant reductions in pain levels compared to control groups. This held true regardless of participants' initial vitamin D levels, and even long-term use did not show considerable improvements in pain outcomes. Interestingly, using active forms of vitamin D also failed to provide the hoped-for relief.
Despite these findings, it’s important to note that vitamin D might still play a role in a broader treatment plan for CLBP. However, as of now, there isn’t enough evidence to suggest that it can independently alleviate the pain. Further investigation is necessary to understand the potential long-term effects and the reasons behind the lack of benefit observed in our study.
9.5
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
8
We examined the impact of vitamin D treatment on patients experiencing back pain related to celiac disease. In one noteworthy case, a 66-year-old man sought help for persistent back and knee pain. After thorough testing, he was diagnosed with celiac disease, alongside vitamin D deficiency and low bone mineral density due to osteomalacia.
The treatment plan included a gluten-free diet and supplementation with vitamin D and calcium. Remarkably, over a span of six months, the patient reported immense relief from symptoms, along with improvements in bone mineral density.
Our findings highlight a significant link between vitamin D supplementation and improvements in musculoskeletal symptoms, particularly for those struggling with celiac disease. While we note that this case does not allow us to make definitive conclusions about vitamin D's isolated effects on back pain, it certainly suggests potential benefits worth considering.
The treatment plan included a gluten-free diet and supplementation with vitamin D and calcium. Remarkably, over a span of six months, the patient reported immense relief from symptoms, along with improvements in bone mineral density.
Our findings highlight a significant link between vitamin D supplementation and improvements in musculoskeletal symptoms, particularly for those struggling with celiac disease. While we note that this case does not allow us to make definitive conclusions about vitamin D's isolated effects on back pain, it certainly suggests potential benefits worth considering.
8
We conducted a randomized controlled trial to investigate how vitamin D supplementation might alleviate lower back pain in patients suffering from lumbar spinal stenosis. This study involved patients with severely low vitamin D levels, specifically under 10 ng/mL. Participants were divided into two groups: one received vitamin D supplements, while the other did not.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
References
- Lee TJ, Tsai RY, Ho CC, Chen CM, Li CP. Updated Meta-analysis Reveals Limited Efficacy of Vitamin D Supplementation in Chronic Low Back Pain. In Vivo. 2024;38:2955. doi:10.21873/invivo.13778
- Bose S, Mohanasundaram K, Rajalakshmi KV, Perumal Kumaresan A, Simon J. An Unusual Mimic of Axial Spondyloarthritis: A Case Report. Cureus. 2024;16:e61441. doi:10.7759/cureus.61441
- V N, Nair GG, Jose BC, Abraham A. Study on Vitamin D Levels in 30 to 40-Year-Old Females With Low Back Pain. Cureus. 2024;16:e54238. doi:10.7759/cureus.54238
- Scaturro D, Vitagliani F, Tomasello S, Sconza C, Respizzi S, et al. Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial. Medicina (Kaunas). 2023;59. doi:10.3390/medicina59122197
- Kim S, Kim SW, Lee BC, Kim DH, Sung DH. Adult-onset hypophosphatemic osteomalacia as a cause of widespread musculoskeletal pain: A retrospective case series of single center experience. World J Clin Cases. 2023;11:7785. doi:10.12998/wjcc.v11.i32.7785
- Ko S, Kim HC, Kwon J. The effectiveness of vitamin D3 supplementation in improving functional outcome of non-surgically treated symptomatic lumbar spinal stenosis: Randomized controlled clinical trial - Pilot study. Medicine (Baltimore). 2023;102:e32672. doi:10.1097/MD.0000000000032672
- Evangelatos G, Kouna K, Iliopoulos A, Fragoulis GE. Musculoskeletal Complications of Celiac Disease: A Case-Based Review. Mediterr J Rheumatol. 2023;34:86. doi:10.31138/mjr.34.1.86
- Dechsupa S, Yingsakmongkol W, Limthongkul W, Singhatanadgige W, Jitjumnong M, et al. Vitamin D Inadequacy Affects Skeletal Muscle Index and Physical Performance in Lumbar Disc Degeneration. Int J Mol Sci. 2023;24. doi:10.3390/ijms24043152
